DEA joins investigation into Hayden Panettiere’s death


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The Drug Enforcement Administration is assisting South Carolina authorities as investigators work to determine what led to actress Hayden Panettiere’s death.

Panettiere, 36, died Sunday at a residence in Greenville. Local police remain in charge of the investigation and said they found no signs of foul play. The coroner has not yet determined her cause or manner of death.

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The New York Times reported that emergency crews found Panettiere in cardiac arrest and were unable to revive her.

According to TMZ, first responders discussed a possible overdose and reported that Narcan, a medication used to reverse opioid overdoses, was found at the residence.

A police report said officers could not determine whether Panettiere had been using drugs or alcohol. Brian Hickerson, her on-again, off-again boyfriend, showed police a bag containing medications she had been taking. In a recent memoir, Panettiere wrote about her history of mental health struggles and substance abuse.

Toxicology testing remains pending.

The DEA has assisted local authorities in other high-profile investigations into drug-related deaths. The agency also became involved after actor Matthew Perry died from a ketamine overdose in 2023. That investigation ultimately resulted in five convictions.

Panettiere was known for roles in “Heroes,” “Nashville” and the “Scream” films.

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Why this story matters

The death of actress Hayden Panettiere is under active investigation by local police and the DEA, with cause of death not yet determined and toxicology results pending.

Cause of death unresolved

The coroner has not determined Panettiere's cause or manner of death, and toxicology testing remains pending, leaving key facts unestablished.

Overdose discussed, not confirmed

According to TMZ, first responders discussed a possible overdose and Narcan was found at the residence, though police could not confirm drug or alcohol use.

DEA involvement follows precedent

The DEA's role mirrors its involvement in the Matthew Perry investigation, which resulted in five convictions after his 2023 ketamine overdose death.

Straight Arrow
Fear No Fact.

Don't just take our word for it.


Center-rated reporting

According to media bias experts at AllSides

AllSides Center-rated reporting May 2026

Transparent and credible

Awarded a perfect reliability rating from NewsGuard

100/100

Welcome back to trustworthy journalism.

Find out more