Fentanyl-stimulant deaths among older adults surge 9,000% in 8 years: Study


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Summary

Challenging the narrative

New research suggests that fentanyl-related overdose deaths among adults aged 65 and older increased by a staggering 9,000% over the past eight years, challenging the narrative that only young Americans are dying from the powerful opioid.

Deadly combinations

The researchers found that most of the fentanyl overdose deaths also included stimulants, with cocaine and methamphetamine proving to be the two most common substances.

4th wave opioid epidemic

The CDC suggests that America’s opioid epidemic has come in three waves since the 1990s. Now, researchers and scholars say we’re in the fourth wave, marked by overdose deaths from fentanyl mixed with other drugs.


Full story

Popular media likes to paint the fentanyl crisis as an epidemic that’s exclusively claiming the lives of young Americans. Now, a new study is challenging the simplified narrative and suggests older adults are just as susceptible to overdosing on the powerful opioid.

A 9,000% increase

During this year’s meeting of the American Society of Anesthesiologists, a team of scientists is presenting their research on opioid use among Americans aged 65 and older. What they found is that over the past eight years, overdose deaths among this age group have increased a staggering 9,000%. 

Those deaths were caused by overdoses from fentanyl mixed with other stimulants, including cocaine and methamphetamines. 

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“A common misconception is that opioid overdoses primarily affect younger people,” said Gab Pasia, the study’s lead author. “Our analysis shows that older adults are also impacted by fentanyl-related deaths and that stimulant involvement has become much more common in this group.”

Pasia and his team looked at nearly 500,000 death certificates, registered between 1999 and 2023, that listed fentanyl as the cause of death. The records were stored in a digital repository managed by the U.S. Centers for Disease Control and Prevention (CDC).

Younger adults, or those aged 25 to 64, represented the vast majority of fentanyl-related deaths, at 387,924. Older adults, meanwhile, accounted for 17,040 deaths. Nevertheless, fentanyl-stimulant deaths among those 65 and older increased from 8.7% in 2015 to 49.9% in 2023, signifying a 9,000% increase.

Deadly mixtures

The researchers noted that toxicology reports from fentanyl-related deaths among older adults usually included another substance, most commonly cocaine and methamphetamine. 

It was also noted that despite older adults being underrepresented in opioid research, the group is particularly vulnerable due to chronic health conditions, the number of medications they are prescribed, and the difficulty their bodies have with processing drugs. 

“National data have shown rising fentanyl-stimulant use among all adults,” said Pasia. “The findings underscore that fentanyl overdoses in older adults are often multi-substance deaths — not due to fentanyl alone — and the importance of sharing drug misuse prevention strategies to older patients.”

The opioid epidemic since the 1990s

According to the CDC, the opioid epidemic has manifested in three waves, beginning with prescription opioid overdoses in the 1990s. That was followed by a significant rise in heroin overdoses in the 2010s, which gave way to a rise in synthetic opioid overdoses around 2013. The American Society of Anesthesiologists says a fourth wave hit around 2015, marked by an increase in deaths related to a mixture of fentanyl and other stimulants. 

“With these trends in mind, it is more important than ever to minimize opioid use in this vulnerable group and use other pain control methods when appropriate,” Richard Wang, one of the study’s co-authors, said. “Proper patient education and regularly reviewing medication lists could help to flatten this terrible trend.”

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Why this story matters

A new study challenges common perceptions of the opioid crisis by demonstrating a dramatic rise in fentanyl-related overdose deaths among older adults, highlighting the need to address drug misuse and prevention strategies for this vulnerable group.

Rising fentanyl overdoses

Fentanyl overdose deaths among Americans aged 65 and older increased by 9,000% over eight years, revealing a critical trend among an often-overlooked population.

Polydrug use

Most fentanyl-related deaths in older adults involved other stimulants like cocaine and methamphetamines, emphasizing that overdoses are frequently due to a combination of substances, not fentanyl alone.

Vulnerability of older adults

Older adults are particularly at risk due to chronic health conditions and medication interactions, yet are often underrepresented in opioid research and prevention efforts.

SAN provides
Unbiased. Straight Facts.

Don’t just take our word for it.


Certified balanced reporting

According to media bias experts at AllSides

AllSides Certified Balanced May 2025

Transparent and credible

Awarded a perfect reliability rating from NewsGuard

100/100

Welcome back to trustworthy journalism.

Find out more

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